Overview

Eurican Herpes 205 is a veterinary vaccine used to immunise pregnant bitches to prevent mortality, clinical signs and lesions in puppies caused by canine herpes virus infections acquired in the first few days of life.

Eurican Herpes 205 contains the active substance canine herpes virus (F205 strain) antigens.

Eurican Herpes 205 is available as a powder and solvent that is made into an emulsion for injection under the skin. It can only be obtained with a prescription.

Eurican Herpes 205 is given as two 1-ml injections. The first injection is given either when the bitch is on heat or 7 – 10 days after the date of mating. The second injection is given 1 to 2 weeks before the expected date of whelping. The bitch should be revaccinated in the same way during each pregnancy.

For more information about using Eurican Herpes 205, see the package leaflet or contact your veterinarian or pharmacist.

Eurican Herpes 205 contains small amounts of canine herpes virus antigens. When injected, this small exposure helps the dog’s immune system to produce antibodies against the canine herpes virus and to neutralize it. Once vaccinated, bitches will, through colostrum, give those antibodies to puppies. When exposed to canine herpes virus later in life, the puppies will either not become infected or have a much less serious infection. Eurican Herpes 205 is intended to protect the puppies from this infection during the first few days of life.

Eurican Herpes 205 has been studied in three laboratory studies and two field trials. In one field trial the serological response (antibody production) was measured. In the other, a study was made of the effect of vaccination on the ability of bitches to breed in an infected kennel. The first laboratory study tested the dose needed to provide protection. The second study was carried out to show the protection of puppies from vaccinated bitches from canine herpe svirus. Here Eurican Herpes 205 was compared with no vaccination (controls). The last one has demonstrating that induction of antibodies is equivalent when bitches are vaccinated the day of heat or 7-10 days after mating.

Eurican Herpes 205 has been studied in three laboratory studies and two field trials. In one field trial the serological response (antibody production) was measured. In the other, a study was made of the effect of vaccination on the ability of bitches to breed in an infected kennel. The first laboratory study tested the dose needed to provide protection. The second study was carried out to show the protection of puppies from vaccinated bitches from canine herpes virus. Here Eurican Herpes 205 was compared with no vaccination (controls). The last one demonstrated that induction of antibodies is equivalent when bitches are vaccinated the day of heat or 7-10 days after mating.

Eurican Herpes 205 showed good protection from canine herpes virus. In the study to show the protection of puppies (from vaccinated bitches) from canine herpes virus, over 80% of the pups from the vaccinated bitches survived.

The injection of Eurican Herpes 205 may cause temporary oedema (fluid under the skin) at the injection site in up to 10% of animals. This side effect usually disappears within one week. Rarely, hypersensitivity (allergic) reactions may occur, which require treatment.

For the full list of side effects and restrictions of Eurican Herpes 205, see the package leaflet.

Eurican Herpes 205 contains mineral oil. Accidental injection may cause severe pain and swelling, particularly if injected into a joint or finger – rarely causing the loss of a finger. If someone is accidentally injected with this product, they must seek immediate medical advice even if only a very small amount is injected. The package leaflet should be taken to the doctor. If pain persists for more than 12 hours after medical examination, the doctor should be contacted again.

The European Medicines Agency decided that Eurican Herpes 205’s benefits are greater than its risks and it can be authorised for use in the EU.

Eurican Herpes 205 received a marketing authorisation valid throughout the EU on 26 March 2001.

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Latest procedure affecting product information: IG/1279

14/08/2020

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Product details

Name of medicine
Eurican Herpes 205
Active substance
Canine herpesvirus (F205 strain) antigens
International non-proprietary name (INN) or common name
Canine herpes vaccine (inactivated subunit)
Species
Dogs
Anatomical therapeutic chemical veterinary (ATCvet) code
QI07AA

Pharmacotherapeutic group

Immunologicals for canidae

Therapeutic indication

Active immunisation of bitches to prevent mortality, clinical signs and lesions in puppies resulting from canine herpes virus infections acquired in the first few days of life.

Authorisation details

EMA product number
EMEA/V/C/000059
Marketing authorisation holder
Boehringer Ingelheim Vetmedica GmbH

Binger Strasse 173
55216 Ingelheim am Rhein
Germany

Marketing authorisation issued
26/03/2001
Revision
12

Assessment history

Topics

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